decreased CD4-positive, alpha beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Zbtb7b<tm2Litt>/Zbtb7b<+>,Tg(Lck-cre)1Cwi/0

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6Cbfbtm1ItanCbfbtm1ItanZbtb7btm2LittZbtb7bTgLckcre1Cwi0Cbfbtm1ItanZbtb7bTgLckcre1CwiZbtb7btm2Litt

decreased CD4-positive, alpha beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Zbtb7b<tm2Litt>/Zbtb7b<+>,Tg(Lck-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448687
• zinc finger and BTB domain containing 7B
  http://metadb.riken.jp/db/mgi_rdf/MGI:102755
• core binding factor beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:99851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cbfb<tm1Itan>/Cbfb<tm1Itan>,Zbtb7b<tm2Litt>/Zbtb7b<+>,Tg(Lck-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cbfb<tm1Itan>|Zbtb7b<+>|Tg(Lck-cre)1Cwi|Zbtb7b<tm2Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Takeshi. Egawa, et.al., ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18776905