decreased CD4-positive, alpha beta T cell number_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag

decreased CD4-positive, alpha beta T cell number_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• FBJ osteosarcoma oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:95574
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Fos<tm7Wag>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Gang. Xiao, et.al., Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22949674