Gang. Xiao, et.al., Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22949674

Gang. Xiao, et.al., Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5449635

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased regulatory T cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0004974IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• increased interleukin-2 secretion_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008687IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased T-helper 1 cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008086IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased tumor latency_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0009828IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased tumor necrosis factor secretion_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008560IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased apoptosis_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0006042IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• decreased CD4-positive, alpha beta T cell number_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag
• decreased interleukin-17 secretion_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008682IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• decreased tumor growth/size_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0003447I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag
• decreased cell proliferation_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000352I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag
• increased interferon-gamma secretion_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008566IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• decreased apoptosis_Tg(CD2-Fos)#Liux/0
  http://metadb.riken.jp/0006043NSTgCD2FosLiux0TgCD2FosLiux
• decreased sensitivity to induced morbidity/mortality_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0009764IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• decreased sensitivity to induced morbidity/mortality_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0009764I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag
• decreased tumor growth/size_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0003447IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• decreased T-helper 17 cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0010220IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased apoptosis_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0006042IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• decreased cell proliferation_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0000352IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• decreased regulatory T cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0004974IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• decreased tumor growth/size_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0003447IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased sensitivity to induced morbidity/mortality_Tg(CD2-Fos)#Liux/0
  http://metadb.riken.jp/0009763NSTgCD2FosLiux0TgCD2FosLiux
• decreased T-helper 2 cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0008091IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased T-helper 1 cell number_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/0008086IC57BL6Pdcd1tm11LiuxPdcd1tm11LiuxPdcd1tm11Liux
• increased apoptosis_Fos<tm7Wag>/Fos<tm7Wag>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0006042I129P2OlaHsdC57BL6DBA2Fostm7WagFostm7WagTgCd4cre1Cwi0TgCd4cre1CwiFostm7Wag
• extended life span_Pdcd1<tm1.1Liux>/Pdcd1<tm1.1Liux>,Tg(MMTV-PyVT)634Mul/0
  http://metadb.riken.jp/0001661IC57BL6FVBNPdcd1tm11LiuxPdcd1tm11LiuxTgMMTVPyVT634Mul0TgMMTVPyVT634MulPdcd1tm11Liux
• increased tumor growth/size_Tg(CD2-Fos)#Liux/0
  http://metadb.riken.jp/0003721NSTgCD2FosLiux0TgCD2FosLiux

class

http://purl.org/net/cito/citesAsAuthority

• Pdcd1<tm1.1Liux>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5449635