decreased CD4-positive, alpha beta T cell number_Sgpl1<tm1(SGPL1)Lex>/Sgpl1<tm1(SGPL1)Lex>

http://metadb.riken.jp/0008075I129S4SvJae129S5SvEvBrdC57BL6JSgpl1tm1SGPL1LexSgpl1tm1SGPL1LexSgpl1tm1SGPL1Lex

decreased CD4-positive, alpha beta T cell number_Sgpl1<tm1(SGPL1)Lex>/Sgpl1<tm1(SGPL1)Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sphingosine phosphate lyase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261415

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sgpl1<tm1(SGPL1)Lex>/Sgpl1<tm1(SGPL1)Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sgpl1<tm1(SGPL1)Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S5/SvEvBrd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Peter. Vogel, et.al., Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions., PloS one, 2009, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/19119317