decreased CD4-positive, alpha beta T cell number_Socs1<tm1Ayos>/Socs1<tm1Ayos>,Tg(Tek-cre)1Ywa/0

http://metadb.riken.jp/0008075I129S4SvJaeC57BL6SJLSocs1tm1AyosSocs1tm1AyosTgTekcre1Ywa0TgTekcre1YwaSocs1tm1Ayos

decreased CD4-positive, alpha beta T cell number_Socs1<tm1Ayos>/Socs1<tm1Ayos>,Tg(Tek-cre)1Ywa/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• suppressor of cytokine signaling 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354910
• transgene insertion 1, Masashi Yanagisawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2450309

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Socs1<tm1Ayos>/Socs1<tm1Ayos>,Tg(Tek-cre)1Ywa/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tek-cre)1Ywa|Socs1<tm1Ayos>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Kentaro. Tanaka, et.al., Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads., Journal of immunology (Baltimore, Md. : 1950), 2008, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/18322180