decreased CD4-positive, alpha beta T cell number_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?

http://metadb.riken.jp/0008075I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal

decreased CD4-positive, alpha beta T cell number_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• transgene insertion 1, Institut Pasteur
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045609
• protease, serine 16 (thymus)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1859181

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)1Pas|Rag2<tm1Fwa>|Prss16<tm1Mal>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, alpha beta T cell number
  http://purl.obolibrary.org/obo/MP_0008075

文献

http://purl.org/net/cito/citesAsAuthority

• Julien. Gommeaux, et.al., Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes., European journal of immunology, 2009, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/19283781