Julien. Gommeaux, et.al., Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes., European journal of immunology, 2009, 39

http://rdf.ncbi.nlm.nih.gov/pubmed/19283781

Julien. Gommeaux, et.al., Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes., European journal of immunology, 2009, 39

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Prss16<tm1Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3843929

class

http://purl.org/net/cito/citesAsAuthority

• Prss16<tm1Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3843929

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal professional antigen presenting cell morphology_Prss16<tm1Mal>/Prss16<tm1Mal>
  http://metadb.riken.jp/0008195I129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalPrss16tm1Mal
• decreased CD4-positive, alpha beta T cell number_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008075I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• abnormal positive T cell selection_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0004919I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• abnormal positive T cell selection_Prss16<tm1Mal>/Prss16<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0004919I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16Rag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasPrss16TgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• thymus hypoplasia_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0001823I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• decreased CD4-positive, alpha beta T cell number_Prss16<tm1Mal>/Prss16<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008075I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16Rag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasPrss16TgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• lymph node hypoplasia_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008101I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• decreased double-positive T cell number_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0005092I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• spleen hypoplasia_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0000694I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• decreased single-positive T cell number_Prss16<tm1Mal>/Prss16<tm1Mal>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008083I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalRag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasTgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• lymph node hypoplasia_Prss16<tm1Mal>/Prss16<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008101I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16Rag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasPrss16TgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal
• abnormal thymus cortex morphology_Prss16<tm1Mal>/Prss16<tm1Mal>
  http://metadb.riken.jp/0002371I129S2SvPasC57BL6Prss16tm1MalPrss16tm1MalPrss16tm1Mal
• decreased single-positive T cell number_Prss16<tm1Mal>/Prss16<+>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(TcraH-Y,TcrbH-Y)1Pas/?
  http://metadb.riken.jp/0008083I129SSvEv129S2SvPasC57BL6Prss16tm1MalPrss16Rag2tm1FwaRag2tm1FwaTgTcraHYTcrbHY1PasPrss16TgTcraHYTcrbHY1PasRag2tm1FwaPrss16tm1Mal

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD39244
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39244