abnormal CD4-positive T cell differentiation_Gt(ROSA)26Sor<tm3(CAG-EYFP)Hze>/Gt(ROSA)26Sor<+>,Stat5a<tm2Mam> Stat5b<tm1Mam>/Del(11Stat5a-Stat5b)1Mam,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0008076I129S6SvEvTacC57BL6C57BL6NCrCBAGtROSA26Sortm3CAGEYFPHzeGtROSA26SorStat5atm2MamStat5btm1MamDel11Stat5aStat5b1MamTgMx1cre1Cgn0Stat5btm1MamGtROSA26Sortm3CAGEYFPHzeGtROSA26SorDel11Stat5aStat5b1MamTgMx1cre1CgnStat5atm2Mam

abnormal CD4-positive T cell differentiation_Gt(ROSA)26Sor<tm3(CAG-EYFP)Hze>/Gt(ROSA)26Sor<+>,Stat5a<tm2Mam> Stat5b<tm1Mam>/Del(11Stat5a-Stat5b)1Mam,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:103036
• deletion, chr 11, Lothar Hennighausen 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:5587830
• signal transducer and activator of transcription 5B
  http://metadb.riken.jp/db/mgi_rdf/MGI:103035
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm3(CAG-EYFP)Hze>/Gt(ROSA)26Sor<+>,Stat5a<tm2Mam> Stat5b<tm1Mam>/Del(11Stat5a-Stat5b)1Mam,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat5b<tm1Mam>|Gt(ROSA)26Sor<tm3(CAG-EYFP)Hze>|Gt(ROSA)26Sor<+>|Del(11Stat5a-Stat5b)1Mam|Tg(Mx1-cre)1Cgn|Stat5a<tm2Mam>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCr * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD4-positive T cell differentiation
  http://purl.obolibrary.org/obo/MP_0008076

文献

http://purl.org/net/cito/citesAsAuthority

• Xuexian O. Yang, et.al., The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation., Nature immunology, 2013, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/23727894