Xuexian O. Yang, et.al., The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation., Nature immunology, 2013, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/23727894

Xuexian O. Yang, et.al., The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation., Nature immunology, 2013, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cish<tm1.1Cdon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544426
• Cish<tm1.2Cdon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544427

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased interleukin-9 secretion_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008711B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• lymph node hyperplasia_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008102B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal respiratory mucosa goblet cell morphology_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0002281B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased lymphocyte cell number_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0005013B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal T-helper 2 cell differentiation_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008092I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• abnormal CD4-positive T cell differentiation_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008076B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal CD4-positive T cell differentiation_Stat6<tm1Gru>/Stat6<tm1Gru>
  http://metadb.riken.jp/0008076C129S2Stat6tm1GruJStat6tm1GruStat6tm1GruStat6tm1Gru
• increased eosinophil cell number_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005011I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• increased interleukin-5 secretion_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008702I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• increased interleukin-5 secretion_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008702B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• spleen hyperplasia_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0000693B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased susceptibility to type I hypersensitivity reaction_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005596I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• increased susceptibility to type I hypersensitivity reaction_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0005596B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal immune system physiology_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0001790B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased interleukin-4 secretion_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008699B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased interleukin-13 secretion_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008672I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• lung inflammation_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0001861B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased eosinophil cell number_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0005011B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal T-helper 2 cell differentiation_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008092B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• abnormal immune system morphology_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0000685B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• pulmonary fibrosis_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0006050B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased interleukin-10 secretion_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008660I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• increased interleukin-13 secretion_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0008672B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• increased interleukin-4 secretion_Cish<tm1.1Cdon>/Cish<tm1.1Cdon>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008699I129S4SvJaeSor129S6SvEvTacC57BL6DBA2Cishtm11CdonCishtm11CdonTgCd4cre1Cwi0Cishtm11CdonTgCd4cre1Cwi
• abnormal CD4-positive T cell differentiation_Gt(ROSA)26Sor<tm3(CAG-EYFP)Hze>/Gt(ROSA)26Sor<+>,Stat5a<tm2Mam> Stat5b<tm1Mam>/Del(11Stat5a-Stat5b)1Mam,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008076I129S6SvEvTacC57BL6C57BL6NCrCBAGtROSA26Sortm3CAGEYFPHzeGtROSA26SorStat5atm2MamStat5btm1MamDel11Stat5aStat5b1MamTgMx1cre1Cgn0Stat5btm1MamGtROSA26Sortm3CAGEYFPHzeGtROSA26SorDel11Stat5aStat5b1MamTgMx1cre1CgnStat5atm2Mam
• increased T cell proliferation_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0005348B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon
• thymus hyperplasia_Cish<tm1.2Cdon>/Cish<tm1.2Cdon>
  http://metadb.riken.jp/0000708B6129S6CgCishtm12CdonCishtm12CdonCishtm12CdonCishtm12Cdon

class

http://purl.org/net/cito/citesAsAuthority

• Cish<tm1.1Cdon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544426
• Cish<tm1.2Cdon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5544427