increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0

http://metadb.riken.jp/0008078I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik

increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 3785, Nigel Killeen
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655480
• CD4 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88335

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd4<tm1Litt>|Tg(Lck-cre)3785Nik|Cd4<tm1Nik>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129X1/SvJ * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008078

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Wang, et.al., Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene., The Journal of experimental medicine, 2001, 194
  http://rdf.ncbi.nlm.nih.gov/pubmed/11748274