Q. Wang, et.al., Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene., The Journal of experimental medicine, 2001, 194

http://rdf.ncbi.nlm.nih.gov/pubmed/11748274

Q. Wang, et.al., Homeostatic competition among T cells revealed by conditional inactivation of the mouse Cd4 gene., The Journal of experimental medicine, 2001, 194

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-cre)3785Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655481
• Cd4<tm1Nik>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2654930
• Tg(Lck-cre)3778Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655490
• Tg(Lck-icre)3779Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655492

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-cre)3785Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655481
• Cd4<tm1Nik>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2654930
• Tg(Lck-cre)3778Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655490
• Tg(Lck-icre)3779Nik
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655492

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, alpha beta T cell number_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0
  http://metadb.riken.jp/0008075I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik
• increased T cell proliferation_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0
  http://metadb.riken.jp/0005348I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik
• abnormal T-helper 2 physiology_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3778Nik/0
  http://metadb.riken.jp/0005466I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3778Nik0Cd4tm1LittTgLckcre3778NikCd4tm1Nik
• abnormal CD4-positive, alpha-beta T cell physiology_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3778Nik/0
  http://metadb.riken.jp/0005463I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3778Nik0Cd4tm1LittTgLckcre3778NikCd4tm1Nik
• abnormal CD4-positive, alpha-beta T cell physiology_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-icre)3779Nik/0
  http://metadb.riken.jp/0005463I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckicre3779Nik0Cd4tm1NikTgLckicre3779NikCd4tm1Litt
• abnormal CD4-positive, alpha-beta T cell physiology_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0
  http://metadb.riken.jp/0005463I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik
• increased T cell apoptosis_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0
  http://metadb.riken.jp/0006413I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik
• decreased T cell proliferation_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3778Nik/0
  http://metadb.riken.jp/0005095I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3778Nik0Cd4tm1LittTgLckcre3778NikCd4tm1Nik
• decreased T cell proliferation_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-icre)3779Nik/0
  http://metadb.riken.jp/0005095I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckicre3779Nik0Cd4tm1NikTgLckicre3779NikCd4tm1Litt
• increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3785Nik/0
  http://metadb.riken.jp/0008078I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3785Nik0Cd4tm1LittTgLckcre3785NikCd4tm1Nik
• abnormal interleukin-4 secretion_Cd4<tm1Litt>/Cd4<tm1Nik>,Tg(Lck-cre)3778Nik/0
  http://metadb.riken.jp/0008698I129S2SvPas129X1SvJC57BL6DBA2Cd4tm1LittCd4tm1NikTgLckcre3778Nik0Cd4tm1LittTgLckcre3778NikCd4tm1Nik