increased CD8-positive, alpha-beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>

http://metadb.riken.jp/0008078I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcraLn3JaeTcraTcrbLn3JaeTcrbTcraRag2tm1FwaTcrbTcraLn3JaeTcrbLn3Jae

increased CD8-positive, alpha-beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• recombination activating gene 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97849
• T cell receptor beta chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98578
• T cell receptor alpha chain
  http://metadb.riken.jp/db/mgi_rdf/MGI:98553

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcra<+>|Rag2<tm1Fwa>|Tcrb<+>|Tcra<Ln3Jae>|Tcrb<Ln3Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008078

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas. Serwold, et.al., Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes., Journal of immunology (Baltimore, Md. : 1950), 2007, 179
  http://rdf.ncbi.nlm.nih.gov/pubmed/17617584