Thomas. Serwold, et.al., Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes., Journal of immunology (Baltimore, Md. : 1950), 2007, 179

http://rdf.ncbi.nlm.nih.gov/pubmed/17617584

Thomas. Serwold, et.al., Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes., Journal of immunology (Baltimore, Md. : 1950), 2007, 179

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tcra<Ln3Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834626
• Tcrb<Ln3Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834628

class

http://purl.org/net/cito/citesAsAuthority

• Tcra<Ln3Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834626
• Tcrb<Ln3Jae>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834628

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased CD8-positive, alpha-beta T cell number_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008078B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• thymus hypoplasia_Tcra<Ln3Jae>/Tcra<+>
  http://metadb.riken.jp/0001823B6CgTcraLn3JaeTcraLn3JaeTcraTcraLn3JaeTcra
• abnormal T cell differentiation_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0002145B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• increased CD8-positive, alpha-beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008078I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcraLn3JaeTcraTcrbLn3JaeTcrbTcraRag2tm1FwaTcrbTcraLn3JaeTcrbLn3Jae
• abnormal double-negative T cell morphology_Tcra<Ln3Jae>/Tcra<+>
  http://metadb.riken.jp/0002407B6CgTcraLn3JaeTcraLn3JaeTcraTcraLn3JaeTcra
• increased CD8-positive, alpha-beta T cell number_Tcra<Ln3Jae>/Tcra<+>
  http://metadb.riken.jp/0008078B6CgTcraLn3JaeTcraLn3JaeTcraTcraLn3JaeTcra
• decreased double-positive T cell number_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0005092B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• increased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0005091I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcrbLn3JaeTcrbRag2tm1FwaTcrbLn3JaeTcrb
• decreased CD4-positive, alpha beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008075I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcrbLn3JaeTcrbRag2tm1FwaTcrbLn3JaeTcrb
• absent gamma-delta T cells_Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008348B6CgTcrbLn3JaeTcrbLn3JaeTcrbTcrbTcrbLn3Jae
• decreased double-positive T cell number_Tcra<Ln3Jae>/Tcra<+>
  http://metadb.riken.jp/0005092B6CgTcraLn3JaeTcraLn3JaeTcraTcraLn3JaeTcra
• abnormal double-negative T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0002407I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcraLn3JaeTcraTcrbLn3JaeTcrbTcraRag2tm1FwaTcrbTcraLn3JaeTcrbLn3Jae
• abnormal double-negative T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0002407I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcrbLn3JaeTcrbRag2tm1FwaTcrbLn3JaeTcrb
• absent gamma-delta T cells_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008348B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• abnormal double-negative T cell morphology_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0002407B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• decreased CD4-positive, alpha beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008075I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcraLn3JaeTcraTcrbLn3JaeTcrbTcraRag2tm1FwaTcrbTcraLn3JaeTcrbLn3Jae
• absent gamma-delta T cells_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008348I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcrbLn3JaeTcrbRag2tm1FwaTcrbLn3JaeTcrb
• absent gamma-delta T cells_Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008348I129SSvEv129S4SvJaeC57BL6Rag2tm1FwaRag2tm1FwaTcraLn3JaeTcraTcrbLn3JaeTcrbTcraRag2tm1FwaTcrbTcraLn3JaeTcrbLn3Jae
• abnormal double-negative T cell morphology_Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0002407B6CgTcrbLn3JaeTcrbLn3JaeTcrbTcrbTcrbLn3Jae
• thymus hypoplasia_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0001823B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• decreased CD4-positive, alpha beta T cell number_Tcra<Ln3Jae>/Tcra<+>,Tcrb<Ln3Jae>/Tcrb<+>
  http://metadb.riken.jp/0008075B6CgTcrbLn3JaeTcraLn3JaeTcraLn3JaeTcraTcrbLn3JaeTcrbTcrbLn3JaeTcraLn3JaeTcrbTcra
• decreased CD4-positive, alpha beta T cell number_Tcra<Ln3Jae>/Tcra<+>
  http://metadb.riken.jp/0008075B6CgTcraLn3JaeTcraLn3JaeTcraTcraLn3JaeTcra