decreased CD8-positive, alpha-beta T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Tnr>/Vav2<tm1Tnr>

http://metadb.riken.jp/0008079I129P2OlaHsd129S2SvPasVav1tm1TybVav1tm1TybVav2tm1TnrVav2tm1TnrVav1tm1TybVav2tm1Tnr

decreased CD8-positive, alpha-beta T cell number_Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Tnr>/Vav2<tm1Tnr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• vav 2 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:102718
• vav 1 oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:98923

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Vav1<tm1Tyb>/Vav1<tm1Tyb>,Vav2<tm1Tnr>/Vav2<tm1Tnr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Vav1<tm1Tyb>|Vav2<tm1Tnr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• G M. Doody, et.al., Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation., Nature immunology, 2001, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/11376342