decreased CD8-positive, alpha-beta T cell number_B2m<tm1Unc>/B2m<tm1Unc>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0

http://metadb.riken.jp/0008079I129P2OlaHsd129S7SvEvBrdC57BL6B2mtm1UncB2mtm1UncIl7rtm11AsinIl7rtm1ImxTgCd8acreAsin0Il7rtm1ImxIl7rtm11AsinB2mtm1UncTgCd8acreAsin

decreased CD8-positive, alpha-beta T cell number_B2m<tm1Unc>/B2m<tm1Unc>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Alfred Singer
  http://metadb.riken.jp/db/mgi_rdf/MGI:4462360
• beta-2 microglobulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:88127
• interleukin 7 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96562

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• B2m<tm1Unc>/B2m<tm1Unc>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il7r<tm1Imx>|Il7r<tm1.1Asin>|B2m<tm1Unc>|Tg(Cd8a*-cre)#Asin

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Tom M. McCaughtry, et.al., Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus., The Journal of experimental medicine, 2012, 209
  http://rdf.ncbi.nlm.nih.gov/pubmed/23109710