Tom M. McCaughtry, et.al., Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus., The Journal of experimental medicine, 2012, 209

http://rdf.ncbi.nlm.nih.gov/pubmed/23109710

Tom M. McCaughtry, et.al., Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus., The Journal of experimental medicine, 2012, 209

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Il2rg<tm1.1Asin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5469000
• Il7r<tm1.1Asin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468999

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, alpha beta T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008075I129S4SvJaeC57BL6Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin
• decreased CD8-positive, alpha-beta T cell number_B2m<tm1Unc>/B2m<tm1Unc>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129P2OlaHsd129S7SvEvBrdC57BL6B2mtm1UncB2mtm1UncIl7rtm11AsinIl7rtm1ImxTgCd8acreAsin0Il7rtm1ImxIl7rtm11AsinB2mtm1UncTgCd8acreAsin
• decreased CD8-positive, alpha-beta T cell number_Il4ra<tm1Sz>/Il4ra<tm1Sz>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129S7SvEvBrdBALBcJC57BL6Il4ratm1SzIl4ratm1SzIl7rtm11AsinIl7rtm1ImxTgCd8acreAsin0Il4ratm1SzTgCd8acreAsinIl7rtm1ImxIl7rtm11Asin
• decreased regulatory T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0004974I129S4SvJaeC57BL6Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin
• decreased CD8-positive, alpha-beta T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129S4SvJaeC57BL6Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin
• decreased CD8-positive, alpha-beta T cell number_Il15<tm1Imx>/Il15<tm1Imx>,Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129S7SvEvBrdC57BL6Il15tm1ImxIl15tm1ImxIl7rtm11AsinIl7rtm1ImxTgCd8acreAsin0TgCd8acreAsinIl15tm1ImxIl7rtm11AsinIl7rtm1Imx
• decreased CD8-positive, alpha-beta T cell number_Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129S7SvEvBrdC57BL6DBA2Il7rtm11AsinIl7rtm1ImxTgCd4cre1Cwi0Il7rtm11AsinIl7rtm1ImxTgCd4cre1Cwi
• decreased NK T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008040I129S4SvJaeC57BL6Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin
• decreased CD4-positive, alpha beta T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129S4SvJaeC57BL6DBA2Il2rgtm11AsinIl2rgtm1WjlTgCd4cre1Cwi0TgCd4cre1CwiIl2rgtm1WjlIl2rgtm11Asin
• decreased CD8-positive, alpha-beta T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129S4SvJaeC57BL6DBA2Il2rgtm11AsinIl2rgtm1WjlTgCd4cre1Cwi0TgCd4cre1CwiIl2rgtm1WjlIl2rgtm11Asin
• decreased CD8-positive, alpha-beta T cell number_B2m<tm1Unc>/B2m<tm1Unc>,Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129P2OlaHsd129S4SvJaeC57BL6B2mtm1UncB2mtm1UncIl2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0TgCd8acreAsinB2mtm1UncIl2rgtm11AsinIl2rgtm1Wjl
• decreased NK T cell number_Il2rg<tm1.1Asin>/Il2rg<tm1Wjl>,Tg(Cd8a*-cre)#Asin/0,Tg(LCKprBCL2)36Sjk/0
  http://metadb.riken.jp/0008040I129S4SvJaeC57BL6Il2rgtm11AsinIl2rgtm1WjlTgCd8acreAsin0TgLCKprBCL236Sjk0TgCd8acreAsinTgLCKprBCL236SjkIl2rgtm11AsinIl2rgtm1Wjl
• decreased CD8-positive, alpha-beta T cell number_Il7r<tm1.1Asin>/Il7r<tm1Imx>,Tg(Cd8a*-cre)#Asin/0
  http://metadb.riken.jp/0008079I129S7SvEvBrdC57BL6Il7rtm11AsinIl7rtm1ImxTgCd8acreAsin0Il7rtm11AsinIl7rtm1ImxTgCd8acreAsin

class

http://purl.org/net/cito/citesAsAuthority

• Il2rg<tm1.1Asin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5469000
• Il7r<tm1.1Asin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468999