decreased CD8-positive, alpha-beta T cell number_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6DBA2FVBNDroshatm1LittDroshatm11LittTgCd4cre1Cwi0Droshatm1LittDroshatm11LittTgCd4cre1Cwi

decreased CD8-positive, alpha-beta T cell number_Drosha<tm1Litt>/Drosha<tm1.1Litt>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• drosha, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261425
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Drosha<tm1Litt>/Drosha<tm1.1Litt>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Drosha<tm1Litt>|Drosha<tm1.1Litt>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Mark M W. Chong, et.al., The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18725527