decreased CD8-positive, alpha-beta T cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

http://metadb.riken.jp/0008079IC57BL6JDBA2JGimap5m1BtlrGimap5m1BtlrTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboGimap5m1Btlr

decreased CD8-positive, alpha-beta T cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 71, Harald von Boehmer
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044559
• GTPase, IMAP family member 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442232

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gimap5<m1Btlr>/Gimap5<m1Btlr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TcraH-Y,TcrbH-Y)71Vbo|Gimap5<m1Btlr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * DBA/2J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD8-positive, alpha-beta T cell number
  http://purl.obolibrary.org/obo/MP_0008079

文献

http://purl.org/net/cito/citesAsAuthority

• Michael J. Barnes, et.al., Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2010, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/20190135