Michael J. Barnes, et.al., Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2010, 184

http://rdf.ncbi.nlm.nih.gov/pubmed/20190135

Michael J. Barnes, et.al., Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2010, 184

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gimap5<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456885

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating interleukin-4 level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008603IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased mature B cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008211IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal B cell physiology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0002459IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• anemia_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0001577IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal bone marrow cell morphology/development_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0002398IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased IgG1 level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008495IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal liver morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000598IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• diarrhea_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005036IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal large intestine crypts of Lieberkuhn morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0004842IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal spleen B cell follicle morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008470IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased IgM level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0001806IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal liver morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000598EIBALBcJC57BL6JorIC3HHeNC57BL6JorC57BL6JDBA2JorIC57BL6JFVBNJorIC57BL6JNODShiLtJGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal colon goblet cell morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0013795IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased B cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005017IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased CD8-positive, alpha-beta T cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008079IC57BL6JDBA2JGimap5m1BtlrGimap5m1BtlrTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboGimap5m1Btlr
• decreased IgG level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0001805IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• colitis_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0002816IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• postnatal growth retardation_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0001732IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal intestinal epithelium morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000488IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased interferon-gamma secretion_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008567IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• intestinal inflammation_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0001858IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased hemoglobin content_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0002874IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal response to transplant_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005671IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased NK T cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008040IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased NK cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008045IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal common lymphocyte progenitor cell morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008249IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased CD8-positive, alpha-beta T cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008079IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased IgG2b level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008497IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• extramedullary hematopoiesis_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000240EIBALBcJC57BL6JorIC3HHeNC57BL6JorC57BL6JDBA2JorIC57BL6JFVBNJorIC57BL6JNODShiLtJGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• increased neutrophil cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000219IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal NK T cell physiology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008042IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• increased hematopoietic stem cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0004809IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased IgG2a level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008496IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal B cell proliferation_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005153IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• thymus atrophy_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0003644IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• increased red blood cell distribution width_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0010067IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• extramedullary hematopoiesis_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000240IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased lymphocyte cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005016IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• thrombocytopenia_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0003179IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• premature death_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0002083IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• cachexia_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005150IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased interleukin-4 secretion_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008700IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased tumor necrosis factor secretion_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008561IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• increased granulocyte number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0000322IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased B cell proliferation_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0005093IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• abnormal common myeloid progenitor cell morphology_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0006410IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased B-1 B cell number_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0004978IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased thymocyte number_Gimap5<m1Btlr>/Gimap5<m1Btlr>,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0000715IC57BL6JDBA2JGimap5m1BtlrGimap5m1BtlrTgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboGimap5m1Btlr
• decreased IgG3 level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008498IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr
• decreased circulating interferon-gamma level_Gimap5<m1Btlr>/Gimap5<m1Btlr>
  http://metadb.riken.jp/0008578IC57BL6JGimap5m1BtlrGimap5m1BtlrGimap5m1Btlr

class

http://purl.org/net/cito/citesAsAuthority

• Gimap5<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4456885

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD35512
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD35512