abnormal CD8-positive, alpha-beta T cell differentiation_B2m<tm1Jae>/B2m<tm1Jae>,Zbtb7b<tm1Litt>/Zbtb7b<tm1.2Litt>

http://metadb.riken.jp/0008080I129S2SvPasC57BL6B2mtm1JaeB2mtm1JaeZbtb7btm1LittZbtb7btm12LittZbtb7btm1LittB2mtm1JaeZbtb7btm12Litt

abnormal CD8-positive, alpha-beta T cell differentiation_B2m<tm1Jae>/B2m<tm1Jae>,Zbtb7b<tm1Litt>/Zbtb7b<tm1.2Litt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• zinc finger and BTB domain containing 7B
  http://metadb.riken.jp/db/mgi_rdf/MGI:102755
• beta-2 microglobulin
  http://metadb.riken.jp/db/mgi_rdf/MGI:88127

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• B2m<tm1Jae>/B2m<tm1Jae>,Zbtb7b<tm1Litt>/Zbtb7b<tm1.2Litt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Zbtb7b<tm1Litt>|B2m<tm1Jae>|Zbtb7b<tm1.2Litt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal CD8-positive, alpha-beta T cell differentiation
  http://purl.obolibrary.org/obo/MP_0008080

文献

http://purl.org/net/cito/citesAsAuthority

• Takeshi. Egawa, et.al., ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18776905