decreased single-positive T cell number_Ppp4c<tm1Tht>/Ppp4c<tm1Tht>,Tg(Lck-cre)548Jxm/0,Tg(TcraTcrb)425Cbn/0

http://metadb.riken.jp/0008083IBALBcC57BL6CBAPpp4ctm1ThtPpp4ctm1ThtTgLckcre548Jxm0TgTcraTcrb425Cbn0Ppp4ctm1ThtTgLckcre548JxmTgTcraTcrb425Cbn

decreased single-positive T cell number_Ppp4c<tm1Tht>/Ppp4c<tm1Tht>,Tg(Lck-cre)548Jxm/0,Tg(TcraTcrb)425Cbn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 548, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176198
• transgene insertion 425, Frank Carbone
  http://metadb.riken.jp/db/mgi_rdf/MGI:3046085
• protein phosphatase 4, catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891763

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ppp4c<tm1Tht>/Ppp4c<tm1Tht>,Tg(Lck-cre)548Jxm/0,Tg(TcraTcrb)425Cbn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ppp4c<tm1Tht>|Tg(Lck-cre)548Jxm|Tg(TcraTcrb)425Cbn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased single-positive T cell number
  http://purl.obolibrary.org/obo/MP_0008083

文献

http://purl.org/net/cito/citesAsAuthority

• Jr-Wen. Shui, et.al., Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17060460