increased T-helper 1 cell number_H2<dlAb1-Ea>/H2<dlAb1-Ea>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

http://metadb.riken.jp/0008086I129S2SvPasC57BL6H2dlAb1EaH2dlAb1EaTgHLADRAHLADRB50101hiKito0TgTRATL3A6TRBTL3A6Kito0H2dlAb1EaTgHLADRAHLADRB50101hiKitoTgTRATL3A6TRBTL3A6Kito

increased T-helper 1 cell number_H2<dlAb1-Ea>/H2<dlAb1-Ea>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion hi, Kouichi Ito
  http://metadb.riken.jp/db/mgi_rdf/MGI:5635423
• transgene insertion, Kouichi Ito
  http://metadb.riken.jp/db/mgi_rdf/MGI:5635433
• histocompatibility-2, MHC
  http://metadb.riken.jp/db/mgi_rdf/MGI:95894

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• H2<dlAb1-Ea>/H2<dlAb1-Ea>,Tg(HLA-DRA,HLA-DRB5*0101)hiKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• H2<dlAb1-Ea>|Tg(HLA-DRA,HLA-DRB5*0101)hiKito|Tg(TRATL3A6,TRBTL3A6)#Kito

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T-helper 1 cell number
  http://purl.obolibrary.org/obo/MP_0008086

文献

http://purl.org/net/cito/citesAsAuthority

• Jacqueline A. Quandt, et.al., Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis., Journal of immunology (Baltimore, Md. : 1950), 2012, 189
  http://rdf.ncbi.nlm.nih.gov/pubmed/22888134