increased plasma cell number_Il6ra<tm1.1(IL6R)Csk>/Il6ra<tm1.1(IL6R)Csk>,Tg(H2-L-IL6)40Csk/0

http://metadb.riken.jp/0008097I129S6SvEvTacC57BL6Il6ratm11IL6RCskIl6ratm11IL6RCskTgH2LIL640Csk0Il6ratm11IL6RCskTgH2LIL640Csk

increased plasma cell number_Il6ra<tm1.1(IL6R)Csk>/Il6ra<tm1.1(IL6R)Csk>,Tg(H2-L-IL6)40Csk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 40, Chugai Pharmaceutical Co Ltd
  http://metadb.riken.jp/db/mgi_rdf/MGI:5556108
• interleukin 6 receptor, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:105304

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Il6ra<tm1.1(IL6R)Csk>/Il6ra<tm1.1(IL6R)Csk>,Tg(H2-L-IL6)40Csk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Il6ra<tm1.1(IL6R)Csk>|Tg(H2-L-IL6)40Csk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased plasma cell number
  http://purl.obolibrary.org/obo/MP_0008097

文献

http://purl.org/net/cito/citesAsAuthority

• Otoya. Ueda, et.al., Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor., Scientific reports, 2013, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/23378927