decreased plasma cell number_Aicda<tm1(cre)Njen>/Aicda<+>,Bcl2l11<tm1Ast>/Bcl2l11<tm1Ast>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

http://metadb.riken.jp/0008098I129S1SvC57BL6Aicdatm1creNjenAicdaBcl2l11tm1AstBcl2l11tm1AstDicer1tm1BdhDicer1tm1BdhAicdaAicdatm1creNjenDicer1tm1BdhBcl2l11tm1Ast

decreased plasma cell number_Aicda<tm1(cre)Njen>/Aicda<+>,Bcl2l11<tm1Ast>/Bcl2l11<tm1Ast>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• BCL2-like 11 (apoptosis facilitator)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1197519
• dicer 1, ribonuclease type III
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177178
• activation-induced cytidine deaminase
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342279

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aicda<tm1(cre)Njen>/Aicda<+>,Bcl2l11<tm1Ast>/Bcl2l11<tm1Ast>,Dicer1<tm1Bdh>/Dicer1<tm1Bdh>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Aicda<+>|Aicda<tm1(cre)Njen>|Dicer1<tm1Bdh>|Bcl2l11<tm1Ast>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased plasma cell number
  http://purl.obolibrary.org/obo/MP_0008098

文献

http://purl.org/net/cito/citesAsAuthority

• Shengli. Xu, et.al., The RNase III enzyme Dicer is essential for germinal center B-cell formation., Blood, 2012, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/22117047