decreased small intestinal villus size_Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Cyp1a1-cre)1Dwi/0

http://metadb.riken.jp/0008142I129P2OlaHsdC57BL6CBALgr4tm11KnisLgr4tm11KnisLgr5tm21CleLgr5tm21CleTgCyp1a1cre1Dwi0Lgr5tm21CleLgr4tm11KnisTgCyp1a1cre1Dwi

decreased small intestinal villus size_Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Cyp1a1-cre)1Dwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Douglas J Winton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052665
• leucine-rich repeat-containing G protein-coupled receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891468
• leucine rich repeat containing G protein coupled receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341817

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Cyp1a1-cre)1Dwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lgr5<tm2.1Cle>|Lgr4<tm1.1Knis>|Tg(Cyp1a1-cre)1Dwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased small intestinal villus size
  http://purl.obolibrary.org/obo/MP_0008142

文献

http://purl.org/net/cito/citesAsAuthority

• Wim. de Lau, et.al., Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling., Nature, 2011, 476
  http://rdf.ncbi.nlm.nih.gov/pubmed/21727895