decreased B-1b cell number_Igh<tm2.1Hws>/Igh<tm2.1Hws>

http://metadb.riken.jp/0008170IBALBcC57BL6NCrlDBA2NCrlIghtm21HwsIghtm21HwsIghtm21Hws

decreased B-1b cell number_Igh<tm2.1Hws>/Igh<tm2.1Hws>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm2.1Hws>/Igh<tm2.1Hws>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh<tm2.1Hws>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * C57BL/6NCrl * DBA/2NCrl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-1b cell number
  http://purl.obolibrary.org/obo/MP_0008170

文献

http://purl.org/net/cito/citesAsAuthority

• Gregory C. Ippolito, et.al., Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production., The Journal of experimental medicine, 2006, 203
  http://rdf.ncbi.nlm.nih.gov/pubmed/16754718