decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>

http://metadb.riken.jp/0008174I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn

decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RAS-related C3 botulinum substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97846
• RAS-related C3 botulinum substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97845
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Rac2<tm1Mddw>|Rac1<tm1Tyb>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Marita J. Walmsley, et.al., Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling., Science (New York, N.Y.), 2003, 302
  http://rdf.ncbi.nlm.nih.gov/pubmed/14564011