Marita J. Walmsley, et.al., Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling., Science (New York, N.Y.), 2003, 302

http://rdf.ncbi.nlm.nih.gov/pubmed/14564011

Marita J. Walmsley, et.al., Critical roles for Rac1 and Rac2 GTPases in B cell development and signaling., Science (New York, N.Y.), 2003, 302

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rac1<tm1Tyb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684419
• Rac1<tm2Tyb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684421

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased transitional stage B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0008190I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn
• arrested B cell differentiation_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0001802I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn
• embryonic lethality, complete penetrance_Rac1<tm2Tyb>/Rac1<tm2Tyb>
  http://metadb.riken.jp/0011092I129S4SvJaeC57BL6Rac1tm2TybRac1tm2TybRac1tm2Tyb
• decreased marginal zone B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0008182I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn
• decreased B-1 B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0004978I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn
• decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0008174I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn
• decreased B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Rac1<tm1Tyb>/Rac1<tm1Tyb>,Rac2<tm1Mddw>/Rac2<tm1Mddw>
  http://metadb.riken.jp/0005017I129P2OlaHsd129SSvEv129S4SvJaeC57BL6Cd19tm1creCgnCd19Rac1tm1TybRac1tm1TybRac2tm1MddwRac2tm1MddwCd19Rac2tm1MddwRac1tm1TybCd19tm1creCgn

class

http://purl.org/net/cito/citesAsAuthority

• Rac1<tm1Tyb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684419
• Rac1<tm2Tyb>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684421