decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ptpn6<tm1Rsky>/Ptpn6<tm1Rsky>

http://metadb.riken.jp/0008174I129P2OlaHsdC57BL6Cd19tm1creCgnCd19Ptpn6tm1RskyPtpn6tm1RskyPtpn6tm1RskyCd19Cd19tm1creCgn

decreased follicular B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Ptpn6<tm1Rsky>/Ptpn6<tm1Rsky>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• protein tyrosine phosphatase, non-receptor type 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:96055

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Ptpn6<tm1Rsky>/Ptpn6<tm1Rsky>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn6<tm1Rsky>|Cd19<+>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Lily I. Pao, et.al., B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity., Immunity, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17600736