decreased follicular B cell number_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0008174I129P2OlaHsdC57BL6Kmt2dtm11KaigKmt2dtm11KaigCd19tm1creCgnCd19Cd19Kmt2dtm11KaigCd19tm1creCgn

decreased follicular B cell number_Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• lysine (K)-specific methyltransferase 2D
  http://metadb.riken.jp/db/mgi_rdf/MGI:2682319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kmt2d<tm1.1Kaig>/Kmt2d<tm1.1Kaig>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Kmt2d<tm1.1Kaig>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Jiyuan. Zhang, et.al., Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis., Nature medicine, 2015, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/26366712