decreased follicular B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0

http://metadb.riken.jp/0008174IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr

decreased follicular B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442
• transgene insertion 1, Robert Brink
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800404
• transgene insertion 5, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053866

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(ML5sHEL)5Ccg|Igh<+>|Tg(IgkHyHEL10)1Rbr|Igh<tm1Rbr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6JSfd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased follicular B cell number
  http://purl.obolibrary.org/obo/MP_0008174

文献

http://purl.org/net/cito/citesAsAuthority

• Tri Giang. Phan, et.al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells., The Journal of experimental medicine, 2003, 197
  http://rdf.ncbi.nlm.nih.gov/pubmed/12668643