Tri Giang. Phan, et.al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells., The Journal of experimental medicine, 2003, 197

http://rdf.ncbi.nlm.nih.gov/pubmed/12668643

Tri Giang. Phan, et.al., B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells., The Journal of experimental medicine, 2003, 197

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igh<tm1Rbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800383
• Tg(IgkHyHEL10)1Rbr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800384

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0002169IC57BL6TgIgkHyHEL101Rbr0TgIgkHyHEL101Rbr
• increased immunoglobulin level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0002461IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgM level_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0002494C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• increased IgM level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0002494IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgA level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0002495IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• abnormal B cell morphology_Igh<tm1Rbr>/Igh<+>
  http://metadb.riken.jp/0004939C57BL6Ightm1RbrIghtm1RbrIghIghtm1RbrIgh
他18件を見る
• abnormal B cell morphology_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0004939C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• abnormal B cell morphology_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0004939IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr
• abnormal B cell morphology_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0004939IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• abnormal B-2 B cell morphology_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0008166C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• abnormal B-2 B cell morphology_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008166IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• decreased follicular B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008174IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr
• decreased marginal zone B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008182IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr
• decreased marginal zone B cell number_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008182IC57BL6TgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg
• increased immature B cell number_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0008214C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• increased immature B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008214IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr
• increased immature B cell number_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008214IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgG1 level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008499IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgG2a level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008500IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgG2b level_Tg(IghelMD4)4Ccg/0
  http://metadb.riken.jp/0008501C57BL6TgIghelMD44CcgTgIghelMD44Ccg0TgIghelMD44Ccg
• increased IgG2b level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008501IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• increased IgG3 level_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0
  http://metadb.riken.jp/0008502IC57BL6Ightm1RbrIghTgIgkHyHEL101Rbr0Ightm1RbrTgIgkHyHEL101RbrIgh
• abnormal B cell anergy_Igh<tm1Rbr>/Igh<+>,Tg(IgkHyHEL10)1Rbr/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008744IC57BL6C57BL6JSfdIghtm1RbrIghTgIgkHyHEL101Rbr0TgML5sHEL5Ccg0TgML5sHEL5CcgIghTgIgkHyHEL101RbrIghtm1Rbr
• abnormal B cell anergy_Tg(IghelMD4)4Ccg/0,Tg(ML5sHEL)5Ccg/0
  http://metadb.riken.jp/0008744IC57BL6TgIghelMD44Ccg0TgML5sHEL5Ccg0TgIghelMD44CcgTgML5sHEL5Ccg

class

http://purl.org/net/cito/citesAsAuthority

• Igh<tm1Rbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800383
• Tg(IgkHyHEL10)1Rbr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3800384