decreased germinal center B cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0008178I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr

decreased germinal center B cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098211
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Pik3cd<tm2.1Tnr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Julia. Rolf, et.al., Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20826752