Julia. Rolf, et.al., Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction., Journal of immunology (Baltimore, Md. : 1950), 2010, 185

http://rdf.ncbi.nlm.nih.gov/pubmed/20826752

Julia. Rolf, et.al., Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction., Journal of immunology (Baltimore, Md. : 1950), 2010, 185

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3cd<tm2.1Tnr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4850049

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal adaptive immunity_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002420I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• decreased IgG1 level_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008495I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• decreased CD4-positive, alpha beta T cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• decreased CD8-positive, alpha-beta T cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• increased IgG1 level_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0008499I129S1Sv129X1SvJPtentm21PppPtentm21PppTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPtentm21Ppp
• abnormal humoral immune response_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001800I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• decreased spleen germinal center number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0008482I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr
• decreased T follicular helper cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0010187I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr
• abnormal humoral immune response_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0001800I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr
• decreased T follicular helper cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0010187I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• increased germinal center B cell number_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0008177I129S1Sv129X1SvJPtentm21PppPtentm21PppTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPtentm21Ppp
• decreased IgG1 level_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0008495I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr
• decreased spleen germinal center size_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008484I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• increased IgE level_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0002497I129P2OlaHsdC57BL6Pik3cdtm21TnrPik3cdtm21TnrCd19tm1creCgnCd19Pik3cdtm21TnrCd19tm1creCgnCd19
• decreased spleen germinal center number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008482I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• increased T follicular helper cell number_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0010186I129S1Sv129X1SvJPtentm21PppPtentm21PppTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPtentm21Ppp
• decreased germinal center B cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>
  http://metadb.riken.jp/0008178I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr
• decreased T cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005018I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr
• decreased germinal center B cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008178I129P2OlaHsdC57BL6DBA2Pik3cdtm21TnrPik3cdtm21TnrTgCd4cre1Cwi0TgCd4cre1CwiPik3cdtm21Tnr

class

http://purl.org/net/cito/citesAsAuthority

• Pik3cd<tm2.1Tnr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4850049

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD46313
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD46313
• CD17887
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD17887