decreased germinal center B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

http://metadb.riken.jp/0008178I129P2OlaHsdC57BL6SJLEbf1tm11RugEbf1tm11RugIghg1tm1creCgnIghg1Ighg1tm1creCgnIghg1Ebf1tm11Rug

decreased germinal center B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy constant gamma 1 (G1m marker)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96446
• early B cell factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95275

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Ighg1<tm1(cre)Cgn>/Ighg1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ighg1<tm1(cre)Cgn>|Ighg1<+>|Ebf1<tm1.1Rug>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Ildiko. Györy, et.al., Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., Genes & development, 2012, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/22431510