Ildiko. Györy, et.al., Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., Genes & development, 2012, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/22431510

Ildiko. Györy, et.al., Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells., Genes & development, 2012, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ebf1<tm1.1Rug>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316286

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgG1 level_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008495IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• arrested B cell differentiation_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0001802IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• arrested B cell differentiation_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Cd79a<tm1(cre)Reth>/Cd79a<+>
  http://metadb.riken.jp/0001802IBALBcC57BL6SJLEbf1tm11RugEbf1tm11RugCd79atm1creRethCd79aCd79aEbf1tm11RugCd79atm1creReth
• increased B cell apoptosis_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008782IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased germinal center B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008178IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased IgG3 level_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008498IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased pre-B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008209IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased marginal zone B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008182IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased marginal zone B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0008182I129P2OlaHsdC57BL6SJLEbf1tm11RugEbf1tm11RugCd19tm1creCgnCd19Cd19tm1creCgnEbf1tm11RugCd19
• decreased spleen germinal center number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008482IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased transitional stage B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008190IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased pre-B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>,Tg(BCL2)#Wehi/0
  http://metadb.riken.jp/0008209IC57BL6C57BL6JWehiSJLSJLJWehiEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aTgBCL2Wehi0Polr2atm1creERT2BbdTgBCL2WehiEbf1tm11RugPolr2a
• decreased germinal center B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Ighg1<tm1(cre)Cgn>/Ighg1<+>
  http://metadb.riken.jp/0008178I129P2OlaHsdC57BL6SJLEbf1tm11RugEbf1tm11RugIghg1tm1creCgnIghg1Ighg1tm1creCgnIghg1Ebf1tm11Rug
• decreased B-1 B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Tg(Cr2-cre)3Cgn/0
  http://metadb.riken.jp/0004978IC57BL6SJLEbf1tm11RugEbf1tm11RugTgCr2cre3Cgn0Ebf1tm11RugTgCr2cre3Cgn
• abnormal germinal center B cell physiology_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008192IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased B cell proliferation_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0005093IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased immature B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>,Tg(BCL2)#Wehi/0
  http://metadb.riken.jp/0008215IC57BL6C57BL6JWehiSJLSJLJWehiEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aTgBCL2Wehi0Polr2atm1creERT2BbdTgBCL2WehiEbf1tm11RugPolr2a
• decreased immature B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0008215IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug
• decreased B-1 B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Cd19<tm1(cre)Cgn>/Cd19<+>
  http://metadb.riken.jp/0004978I129P2OlaHsdC57BL6SJLEbf1tm11RugEbf1tm11RugCd19tm1creCgnCd19Cd19tm1creCgnEbf1tm11RugCd19
• decreased marginal zone B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Tg(Cr2-cre)3Cgn/0
  http://metadb.riken.jp/0008182IC57BL6SJLEbf1tm11RugEbf1tm11RugTgCr2cre3Cgn0Ebf1tm11RugTgCr2cre3Cgn
• increased B cell number_Ebf1<tm1.1Rug>/Ebf1<tm1.1Rug>,Polr2a<tm1(cre/ERT2)Bbd>/Polr2a<+>
  http://metadb.riken.jp/0005014IC57BL6SJLEbf1tm11RugEbf1tm11RugPolr2atm1creERT2BbdPolr2aPolr2aPolr2atm1creERT2BbdEbf1tm11Rug

class

http://purl.org/net/cito/citesAsAuthority

• Ebf1<tm1.1Rug>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5316286