decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Y,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>

http://metadb.riken.jp/0008178I129S1Sv129S4SvJae129X1SvJBALBcSh2d1atm1CptYTcraJtm1TgiTcraJtm1TgiTcraJtm1TgiSh2d1atm1Cpt

decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Y,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• T cell receptor alpha, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:98555
• SH2 domain containing 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328352

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sh2d1a<tm1Cpt>/Y,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tcra-J<tm1Tgi>|Sh2d1a<tm1Cpt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Cynthia. Detre, et.al., SAP expression in invariant NKT cells is required for cognate help to support B-cell responses., Blood, 2012, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/22613797