Cynthia. Detre, et.al., SAP expression in invariant NKT cells is required for cognate help to support B-cell responses., Blood, 2012, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/22613797

Cynthia. Detre, et.al., SAP expression in invariant NKT cells is required for cognate help to support B-cell responses., Blood, 2012, 120

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sh2d1a<tm2.1Cpt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444609

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgG level_Sh2d1a<tm2.1Cpt>/Sh2d1a<tm2.1Cpt>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001805IC57BL6C57BL6NTacSh2d1atm21CptSh2d1atm21CptGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal germinal center B cell morphology_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008176I129S4SvJaeBALBcSh2d1atm1CptYSh2d1atm1Cpt
• decreased IgG level_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0001805I129S4SvJaeBALBcSh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• abnormal NK T cell physiology_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008042I129S4SvJaeC57BL6Sh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• decreased IgG level_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0001805I129S4SvJaeBALBcSh2d1atm1CptYSh2d1atm1Cpt
• abnormal humoral immune response_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0001800I129S4SvJaeC57BL6Sh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• decreased IgM level_Sh2d1a<tm2.1Cpt>/Sh2d1a<tm2.1Cpt>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001806IC57BL6C57BL6NTacSh2d1atm21CptSh2d1atm21CptGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal immunoglobulin level_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0002490I129S4SvJaeC57BL6Sh2d1atm1CptYSh2d1atm1Cpt
• abnormal germinal center B cell morphology_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008176I129S4SvJaeBALBcSh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Y,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>
  http://metadb.riken.jp/0008178I129S1Sv129S4SvJae129X1SvJBALBcSh2d1atm1CptYTcraJtm1TgiTcraJtm1TgiTcraJtm1TgiSh2d1atm1Cpt
• decreased NK T cell number_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008040I129S4SvJaeBALBcSh2d1atm1CptYSh2d1atm1Cpt
• abnormal germinal center B cell physiology_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008192I129S4SvJaeC57BL6Sh2d1atm1CptYSh2d1atm1Cpt
• abnormal NK T cell physiology_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008042I129S4SvJaeC57BL6Sh2d1atm1CptYSh2d1atm1Cpt
• decreased NK T cell number_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008040I129S4SvJaeC57BL6Sh2d1atm1CptYSh2d1atm1Cpt
• abnormal humoral immune response_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0001800I129S4SvJaeC57BL6Sh2d1atm1CptYSh2d1atm1Cpt
• decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>
  http://metadb.riken.jp/0008178I129S1Sv129S4SvJae129X1SvJBALBcSh2d1atm1CptSh2d1atm1CptTcraJtm1TgiTcraJtm1TgiSh2d1atm1CptTcraJtm1Tgi
• decreased IgG level_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>
  http://metadb.riken.jp/0001805I129S1Sv129S4SvJae129X1SvJBALBcSh2d1atm1CptSh2d1atm1CptTcraJtm1TgiTcraJtm1TgiSh2d1atm1CptTcraJtm1Tgi
• decreased IgG level_Sh2d1a<tm1Cpt>/Y,Tcra-J<tm1Tgi>/Tcra-J<tm1Tgi>
  http://metadb.riken.jp/0001805I129S1Sv129S4SvJae129X1SvJBALBcSh2d1atm1CptYTcraJtm1TgiTcraJtm1TgiTcraJtm1TgiSh2d1atm1Cpt
• decreased NK T cell number_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008040I129S4SvJaeBALBcSh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• abnormal humoral immune response_Sh2d1a<tm2.1Cpt>/Sh2d1a<tm2.1Cpt>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001800IC57BL6C57BL6NTacSh2d1atm21CptSh2d1atm21CptGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal germinal center B cell physiology_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008192I129S4SvJaeC57BL6Sh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Y
  http://metadb.riken.jp/0008178I129S4SvJaeBALBcSh2d1atm1CptYSh2d1atm1Cpt
• decreased IgG level_Sh2d1a<tm2.1Cpt>/Y,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001805IC57BL6C57BL6NTacSh2d1atm21CptYGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal humoral immune response_Sh2d1a<tm2.1Cpt>/Y,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001800IC57BL6C57BL6NTacSh2d1atm21CptYGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• decreased NK T cell number_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008040I129S4SvJaeC57BL6Sh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• decreased IgM level_Sh2d1a<tm2.1Cpt>/Y,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0001806IC57BL6C57BL6NTacSh2d1atm21CptYGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal germinal center B cell physiology_Sh2d1a<tm2.1Cpt>/Sh2d1a<tm2.1Cpt>,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008192IC57BL6C57BL6NTacSh2d1atm21CptSh2d1atm21CptGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• abnormal immunoglobulin level_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0002490I129S4SvJaeC57BL6Sh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt
• abnormal germinal center B cell physiology_Sh2d1a<tm2.1Cpt>/Y,Gt(ROSA)26Sor<tm9(cre/ESR1)Arte>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0008192IC57BL6C57BL6NTacSh2d1atm21CptYGtROSA26Sortm9creESR1ArteGtROSA26SorGtROSA26Sortm9creESR1ArteGtROSA26SorSh2d1atm21Cpt
• decreased germinal center B cell number_Sh2d1a<tm1Cpt>/Sh2d1a<tm1Cpt>
  http://metadb.riken.jp/0008178I129S4SvJaeBALBcSh2d1atm1CptSh2d1atm1CptSh2d1atm1Cpt

class

http://purl.org/net/cito/citesAsAuthority

• Sh2d1a<tm2.1Cpt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444609