decreased germinal center B cell number_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?

http://metadb.riken.jp/0008178IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn

decreased germinal center B cell number_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• REV3 like, DNA directed polymerase zeta catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1337131
• transgene insertion 3, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:3708319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rev3l<tm1Rsky>|Rev3l<tm1.1Rsky>|Tg(Cr2-cre)3Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased germinal center B cell number
  http://purl.obolibrary.org/obo/MP_0008178

文献

http://purl.org/net/cito/citesAsAuthority

• Dominik. Schenten, et.al., Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19204108