Dominik. Schenten, et.al., Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability., The Journal of experimental medicine, 2009, 206

http://rdf.ncbi.nlm.nih.gov/pubmed/19204108

Dominik. Schenten, et.al., Pol zeta ablation in B cells impairs the germinal center reaction, class switch recombination, DNA break repair, and genome stability., The Journal of experimental medicine, 2009, 206

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rev3l<tm1.1Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837725
• Rev3l<tm1Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837724

class

http://purl.org/net/cito/citesAsAuthority

• Rev3l<tm1.1Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837725
• Rev3l<tm1Rsky>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837724

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased IgG1 level_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0008495IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn
• abnormal somatic hypermutation frequency_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0004815IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn
• spontaneous chromosome breakage_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0004029IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn
• decreased germinal center B cell number_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0008178IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn
• abnormal class switch recombination_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0004816IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn
• decreased B cell proliferation_Rev3l<tm1Rsky>/Rev3l<tm1.1Rsky>,Tg(Cr2-cre)3Cgn/?
  http://metadb.riken.jp/0005093IC57BL6Rev3ltm1RskyRev3ltm11RskyTgCr2cre3CgnRev3ltm1RskyRev3ltm11RskyTgCr2cre3Cgn