increased marginal zone B cell number_Grk2<tm1Gwd>/Grk2<tm1Gwd>,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0008181I129BALBcC57BL6Grk2tm1GwdGrk2tm1GwdCd79atm1creRethCd79aGrk2tm1GwdCd79aCd79atm1creReth

increased marginal zone B cell number_Grk2<tm1Gwd>/Grk2<tm1Gwd>,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• G protein-coupled receptor kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:87940
• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grk2<tm1Gwd>/Grk2<tm1Gwd>,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grk2<tm1Gwd>|Cd79a<+>|Cd79a<tm1(cre)Reth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008181

文献

http://purl.org/net/cito/citesAsAuthority

• Tal I. Arnon, et.al., GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood., Science (New York, N.Y.), 2011, 333
  http://rdf.ncbi.nlm.nih.gov/pubmed/21960637