increased marginal zone B cell number_Gt(ROSA)26Sor<tm2(Lmp1/CD40)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

http://metadb.riken.jp/0008181I129P2OlaHsdBALBcC57BL6GtROSA26Sortm2Lmp1CD40UzsGtROSA26SorCd19tm1creCgnCd19Cd19tm1creCgnGtROSA26Sortm2Lmp1CD40UzsGtROSA26SorCd19

increased marginal zone B cell number_Gt(ROSA)26Sor<tm2(Lmp1/CD40)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(Lmp1/CD40)Uzs>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<tm1(cre)Cgn>|Gt(ROSA)26Sor<tm2(Lmp1/CD40)Uzs>|Gt(ROSA)26Sor<+>|Cd19<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased marginal zone B cell number
  http://purl.obolibrary.org/obo/MP_0008181

文献

http://purl.org/net/cito/citesAsAuthority

• Cornelia. Hömig-Hölzel, et.al., Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-kappaB pathway and promotes lymphomagenesis., The Journal of experimental medicine, 2008, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/18490492