absent B-1 B cells_Lyn<tm1Ard>/Lyn<tm1Ard>,Tg(IghelMD4)4Ccg/0

http://metadb.riken.jp/0008202I129P2OlaHsdC57BL6Lyntm1ArdLyntm1ArdTgIghelMD44Ccg0Lyntm1ArdTgIghelMD44Ccg

absent B-1 B cells_Lyn<tm1Ard>/Lyn<tm1Ard>,Tg(IghelMD4)4Ccg/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892
• transgene insertion 4, Christopher C Goodnow
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lyn<tm1Ard>/Lyn<tm1Ard>,Tg(IghelMD4)4Ccg/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyn<tm1Ard>|Tg(IghelMD4)4Ccg

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent B-1 B cells
  http://purl.obolibrary.org/obo/MP_0008202

文献

http://purl.org/net/cito/citesAsAuthority

• R J. Cornall, et.al., Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection., Immunity, 1998, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/9586639