decreased B-2 B cell number_Sppl2a<tm1Basc>/Sppl2a<tm1Basc>

http://metadb.riken.jp/0008207I129S1Sv129X1SvJC57BL6NCrlSppl2atm1BascSppl2atm1BascSppl2atm1Basc

decreased B-2 B cell number_Sppl2a<tm1Basc>/Sppl2a<tm1Basc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal peptide peptidase like 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1913802

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sppl2a<tm1Basc>/Sppl2a<tm1Basc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sppl2a<tm1Basc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased B-2 B cell number
  http://purl.obolibrary.org/obo/MP_0008207

文献

http://purl.org/net/cito/citesAsAuthority

• Janna. Schneppenheim, et.al., The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain., The Journal of experimental medicine, 2013, 210
  http://rdf.ncbi.nlm.nih.gov/pubmed/23267015