increased mature B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm5(Map3k14)Rsky>/Gt(ROSA)26Sor<tm5(Map3k14)Rsky>

http://metadb.riken.jp/0008210I129P2OlaHsdC57BL6Cd19tm1creCgnCd19GtROSA26Sortm5Map3k14RskyGtROSA26Sortm5Map3k14RskyCd19GtROSA26Sortm5Map3k14RskyCd19tm1creCgn

increased mature B cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm5(Map3k14)Rsky>/Gt(ROSA)26Sor<tm5(Map3k14)Rsky>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1(cre)Cgn>/Cd19<+>,Gt(ROSA)26Sor<tm5(Map3k14)Rsky>/Gt(ROSA)26Sor<tm5(Map3k14)Rsky>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd19<+>|Gt(ROSA)26Sor<tm5(Map3k14)Rsky>|Cd19<tm1(cre)Cgn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008210

文献

http://purl.org/net/cito/citesAsAuthority

• Yoshiteru. Sasaki, et.al., NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18663224