decreased mature B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>

http://metadb.riken.jp/0008211I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft

decreased mature B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD19 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88319
• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyn<tm1Sor>|Cd19<tm1Tft>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• M. Hasegawa, et.al., A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2001, 167
  http://rdf.ncbi.nlm.nih.gov/pubmed/11509585