M. Hasegawa, et.al., A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2001, 167

http://rdf.ncbi.nlm.nih.gov/pubmed/11509585

M. Hasegawa, et.al., A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 2001, 167

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased anti-double stranded DNA antibody level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004762I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• increased susceptibility to systemic lupus erythematosus_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004801I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• increased IgG2b level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0008501I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• increased IgG level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0002493I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased B-1 B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0004978I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• decreased B-1 B cell number_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004978I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• glomerulonephritis_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0002743I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased mature B cell number_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0008211I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased B cell number_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0005017I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased susceptibility to systemic lupus erythematosus_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004802I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased B cell proliferation_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0005093I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased B-1 B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004978I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0005017I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• increased IgM level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0002494I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased IgM level_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0001806I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• increased IgG1 level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0008499I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased B cell proliferation_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0005093I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• decreased mature B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0008211I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased IgG2b level_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0008497I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• enlarged spleen_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0000691I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• enlarged spleen_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0000691I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• increased IgA level_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0002495I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• increased B cell proliferation_Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0005154I129S4SvJaeSorC57BL6Lyntm1SorLyntm1SorLyntm1Sor
• decreased IgG1 level_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0008495I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• decreased anti-double stranded DNA antibody level_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0004798I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased B cell number_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0005017I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• abnormal humoral immune response_Cd19<tm1Tft>/Cd19<tm1Tft>,Lyn<tm1Sor>/Lyn<tm1Sor>
  http://metadb.riken.jp/0001800I129S4SvJaeSorC57BL6Cd19tm1TftCd19tm1TftLyntm1SorLyntm1SorLyntm1SorCd19tm1Tft
• decreased IgA level_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0001807I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft
• abnormal humoral immune response_Cd19<tm1Tft>/Cd19<tm1Tft>
  http://metadb.riken.jp/0001800I129C57BL6Cd19tm1TftCd19tm1TftCd19tm1Tft