decreased mature B cell number_Grb2<tm1Lnit>/Grb2<tm1Lnit>,Cd79a<tm1(cre)Reth>/Cd79a<+>

http://metadb.riken.jp/0008211IBALBcBALBcJGrb2tm1LnitGrb2tm1LnitCd79atm1creRethCd79aCd79aGrb2tm1LnitCd79atm1creReth

decreased mature B cell number_Grb2<tm1Lnit>/Grb2<tm1Lnit>,Cd79a<tm1(cre)Reth>/Cd79a<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• CD79A antigen (immunoglobulin-associated alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:101774
• growth factor receptor bound protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:95805

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grb2<tm1Lnit>/Grb2<tm1Lnit>,Cd79a<tm1(cre)Reth>/Cd79a<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cd79a<+>|Grb2<tm1Lnit>|Cd79a<tm1(cre)Reth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: BALB/c * BALB/cJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mature B cell number
  http://purl.obolibrary.org/obo/MP_0008211

文献

http://purl.org/net/cito/citesAsAuthority

• Jochen A. Ackermann, et.al., Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+ signalling., The EMBO journal, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21427701