absent mature B cells_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>

http://metadb.riken.jp/0008212I129P2OlaHsdIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvIghJtm1JkbvIgkctm1Jkbv

absent mature B cells_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• immunoglobulin heavy chain, joining region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96461
• immunoglobulin kappa constant
  http://metadb.riken.jp/db/mgi_rdf/MGI:96495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igh-J<tm1Jkbv>|Igkc<tm1Jkbv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent mature B cells
  http://purl.obolibrary.org/obo/MP_0008212

文献

http://purl.org/net/cito/citesAsAuthority

• M J. Mendez, et.al., Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice., Nature genetics, 1997, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/9020839
• L L. Green, et.al., Regulation of B cell development by variable gene complexity in mice reconstituted with human immunoglobulin yeast artificial chromosomes., The Journal of experimental medicine, 1998, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/9687526