M J. Mendez, et.al., Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice., Nature genetics, 1997, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/9020839

M J. Mendez, et.al., Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice., Nature genetics, 1997, 15

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(IGK@yK2)J23.1Jkbv
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802714
• Tg(IGH@yH2)J9.2Jkbv
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802713

class

http://purl.org/net/cito/citesAsAuthority

• Tg(IGK@yK2)J23.1Jkbv
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802714
• Tg(IGH@yH2)J9.2Jkbv
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802713

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immunoglobulin level_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0
  http://metadb.riken.jp/0002490I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv
• absent mature B cells_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>
  http://metadb.riken.jp/0008212I129P2OlaHsdIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvIghJtm1JkbvIgkctm1Jkbv
• abnormal B cell morphology_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0
  http://metadb.riken.jp/0004939I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv
• abnormal immunoglobulin light chain V-J recombination_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0
  http://metadb.riken.jp/0008761I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv
• abnormal immunoglobulin heavy chain V(D)J recombination_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0
  http://metadb.riken.jp/0008760I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv
• increased mature B cell number_Igh-J<tm1Jkbv>/Igh-J<tm1Jkbv>,Igkc<tm1Jkbv>/Igkc<tm1Jkbv>,Tg(IGH@yH2)J9.2Jkbv/0,Tg(IGK@yK2)J23.1Jkbv/0
  http://metadb.riken.jp/0008210I129P2OlaHsdC57BL6JIghJtm1JkbvIghJtm1JkbvIgkctm1JkbvIgkctm1JkbvTgIGHyH2J92Jkbv0TgIGKyK2J231Jkbv0Igkctm1JkbvIghJtm1JkbvTgIGKyK2J231JkbvTgIGHyH2J92Jkbv